| | Cancer | Colon Cancer How many people did colon cancer kill? Colon cancer is the third leading cause of cancer death in the United States, with about 53,200 deaths in 2020. Colon Cancer - Related Articles What Can a Woman Expect at a Colorectal Exam? Women With Colon Cancer Signs & Symptoms of Colon Cancer Stage 4 Where Does Colon Cancer Spread? Foods That Prevent Colon Cancer How many people die from colon cancer each year? What Is Metastatic Colon Cancer?