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Black Spots on Arms: Causes from Sun Damage to Medical Conditions
Dark spots on arms (hyperpigmentation) have diverse etiologies:
1. Solar Lentigines (Sun/Age Spots)
- UV‑induced melanocyte hyperplasia.
- Light brown to black, 2–20 mm, on sun‑exposed sites (forearms, hands).
- Benign; increase with age/cumulative UV.
2. Post‑Inflammatory Hyperpigmentation (PIH)
- After acne, eczema, burns, cuts, insect bites.
- Darker skin types more prone.
- Fades slowly (months–years) with sun protection.
3. Drug‑Induced
- OCPs, HRT, antimalarials (chloroquine), amiodarone, tetracyclines, chemotherapeutics.
- Often diffuse or localized; may reverse after discontinuation.
4. Medical Conditions
- Acanthosis Nigricans: Velvety hyperpigmentation (axilla, neck) – insulin resistance.
- Addison’s Disease: Generalized + palmar creases, knuckles – ACTH/MSH excess.
- Hemochromatosis: Bronze skin – iron deposition.
- Porphyria Cutanea Tarda: Photosensitivity, blisters, hyperpigmentation on hands.
5. Melanoma Warning Signs (ABCDE)
- Asymmetry, Border irregular, Color variation, Diameter >6 mm, Evolving.
- New or changing spot → dermatologist urgently.
Management
- Broad‑spectrum SPF 30+ daily.
- Topical: hydroquinone (4%), retinoids, azelaic acid, vitamin C, niacinamide, cysteamine.
- Procedures: chemical peels, laser (Q‑switched Nd:YAG, fractional), IPL.
- Treat underlying condition (insulin resistance, iron overload).
Any suspicious lesion—biopsy. Early melanoma detection saves lives.
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