Three Phases of Breathing: Inspiration, Gas Exchange, Expiration

Respiration comprises three continuous phases:

  1. Inspiration (Inhalation) – Diaphragm contracts (flattens), external intercostals lift ribs → thoracic volume ↑ → intrapulmonary pressure ↓ → air flows in.
  2. Gas Exchange (External Respiration) – At alveolar‑capillary membrane: O₂ diffuses into blood (binds Hb), CO₂ diffuses out (driven by partial pressure gradients).
  3. Expiration (Exhalation) – Diaphragm relaxes (domes up), intercostals relax → volume ↓ → pressure ↑ → air flows out. (Passive at rest; active with forced expiration using internal intercostals/abdominals.)

Cycle repeats 12–20 times/min at rest.

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