Ciprofloxacin for STIs: Which Infections It Treats
Ciprofloxacin (a fluoroquinolone) has limited current use for STIs due to widespread resistance.
- Gonorrhea: Not recommended—high‐level resistance globally.
- Chlamydia: Not first‑line (doxycycline/azithromycin preferred); cipro has poor efficacy.
- Chancroid: Alternative if macrolides fail (H. ducreyi usually susceptible).
- Non‑gonococcal urethritis (NGU): Not standard; M. genitalium often resistant.
- Syphilis: No role—penicillin is sole curative.
- LGV: Doxycycline is standard; cipro not recommended.
Current CDC/WHO guidelines favor ceftriaxone + doxycycline for gonorrhea/chlamydia. Always confirm local susceptibility patterns.
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