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Chronic Inflammatory Demyelinating Polyneuropathy (CIPD) Prognosis: Factors Influencing Recovery
CIPD (more commonly CIDP) prognosis varies. Key determinants:
- Early Diagnosis & Treatment: Prevents axonal loss; improves remission rates.
- Disease Severity at Presentation: Mild sensory-predominant forms fare better than severe motor/autonomic involvement.
- Phenotype: Typical (progressive/relapsing) vs. atypical (Lewis-Sumner, pure sensory, pure motor) – treatment responsiveness differs.
- Comorbidities: Diabetes, vasculitis, malignancy worsen outlook.
- Treatment Response: IVIG, corticosteroids, plasma exchange, immunosuppressants. Sustained responders often regain function; refractory cases accumulate disability.
Regular neuromuscular follow-up with objective strength/functional measures guides therapy adjustments.
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