Prolixin (Fluphenazine): Uses, Dosage & Side Effects

Prolixin is a medication prescribed to treat schizophrenia and acute mania in bipolar disorder. A brand name for fluphenazine, Prolixin is classified as a typical anti-psychotic drug in the category of phenothiazines.

Types

• Prolixin is available in tablets in various dosages as well as liquid and injectable form. Many patients tolerate the injection better than the oral versons. An injected dose can last two to four weeks, unlike the tablets or liquid, which must be taken at least once daily.

Efficacy

• According to the National Alliance for the Mentally Ill (NAMI), Prolixin is effective for about 60 percent of patients. This is true for most anti-psychotic medications.

Function

• Prolixin blocks the effects of the chemical dopamine in the brain, which may be higher than normal in people with schizophrenia or other psychotic disorders.

Common Side Effects

• The most common side effects associated with Prolixin include constipation, dizziness, drowsiness, dry mouth and vision changes.

Serious Side Effects

• Rarely, Prolixin can cause tardive dyskinesia, a disorder resulting in uncontrollable movements of the face or body. This disorder may be permanent. Prolixin also can lead to neuroleptic malignant syndrome, a neurological disorder that can be life-threatening.

Contraindications

• Prolixin is linked to pneumonia, cardiac failure or sudden death in older adults with dementia. The drug should not be administered to these patients.