Depakote (Valproic Acid): Understanding Long-Term Risks & Side Effects

While Divalproex Sodium, commonly known as Depakote, may be one of the best medications on the market for illnesses such as bipolar disorder, it isn't without its side effects. Even the best medications have their side effects, warnings and interactions. For consumers interested in talking to their doctors about Depakote, a little information regarding long-term side effects is worth looking into.

Irregular Menstruation

• Long-term Depakote use has also been linked to irregular menstruation.

PCOS

• Some women using the drug over a long period of time have been known to develop PCOS, or polycystic ovary syndrome.

Bone Loss

• Bone loss is a side effect of taking Depakote for many years. Supplements such as calcium and vitamin D can combat this.

Bone Density Test

• Depakote users should talk to their doctors about getting a bone density test if they have been taking the drug for more than 5 years.

Solution

• Any side effect that becomes intolerable, difficult to deal with or detrimental to the quality of life should be discussed with a qualified medical professional.