What does marked mean in medical terms?

Marked in medical terms means:

- Pronounced or severe.

- Clearly noticeable or evident.

- Of substantial degree or intensity.

For example,

- "The patient had marked dyspnea on exertion" means the patient had severe shortness of breath when they exerted themselves.

- "There was marked swelling in the patient's right leg" means the swelling in the patient's right leg was very noticeable and significant.