“Sig” on Prescriptions: Latin Origin and Meaning

Sig (or Sig.) is from Latin signa = “write” or “label” (imperative of signare).

Usage

On a prescription, Sig: precedes the patient directions (dose, route, frequency, duration).

Examples

• Sig: Take 1 tablet by mouth twice daily with food.
• Sig: Apply thin layer to affected area at bedtime.
• Sig: 1–2 puffs every 4–6 hours as needed for wheezing.

Related

• Rx = recipe (take thou) – superscription.
• Disp. = dispensa – quantity to dispense.
• Ref. = refills authorized.

Standardized by NCPDP SCRIPT for e-prescribing.