Group B Strep (GBS) Infection: High-Risk Groups and Complications

Populations Most at Risk

• Newborns: Pneumonia, meningitis, sepsis if mother is colonized during pregnancy.
• Pregnant Women: Chorioamnionitis, postpartum endometritis.
• Immunocompromised: Diabetes, HIV/AIDS, cancer patients.
• Post-Surgical Patients: Especially with implanted devices (pacemakers, artificial joints).
• IV Drug Users: Particularly if sharing needles/paraphernalia.

Screening and intrapartum antibiotics for colonized mothers significantly reduce neonatal GBS disease.