Thyroid Gland: Functions, Hormones & Health Importance

Anatomy & Hormones

Butterfly-shaped gland in the anterior neck. Produces:

  • Thyroxine (T4) – prohormone, major secretory product.
  • Triiodothyronine (T3) – biologically active form (mostly from peripheral T4 conversion).

Regulation

Hypothalamus (TRH) → Pituitary (TSH) → Thyroid (T4/T3). Negative feedback by T3/T4 on pituitary/hypothalamus.

Systemic Effects

  • Basal metabolic rate
  • Heart rate & contractility
  • Blood pressure
  • Body temperature
  • GI motility
  • Bone turnover
  • Fertility & menstrual regularity
  • Mood, cognition, energy

Disorders

  • Hyperthyroidism: Weight loss, tachycardia, anxiety, heat intolerance, diarrhea.
  • Hypothyroidism: Weight gain, fatigue, cold intolerance, constipation, depression.

Thyroid dysfunction is common and treatable. See a doctor for symptoms or screening if at risk.

Thyroid Disease - Related Articles