Thyroid Gland: Functions, Hormones & Health Importance
Anatomy & Hormones
Butterfly-shaped gland in the anterior neck. Produces:
- Thyroxine (T4) – prohormone, major secretory product.
- Triiodothyronine (T3) – biologically active form (mostly from peripheral T4 conversion).
Regulation
Hypothalamus (TRH) → Pituitary (TSH) → Thyroid (T4/T3). Negative feedback by T3/T4 on pituitary/hypothalamus.
Systemic Effects
- Basal metabolic rate
- Heart rate & contractility
- Blood pressure
- Body temperature
- GI motility
- Bone turnover
- Fertility & menstrual regularity
- Mood, cognition, energy
Disorders
- Hyperthyroidism: Weight loss, tachycardia, anxiety, heat intolerance, diarrhea.
- Hypothyroidism: Weight gain, fatigue, cold intolerance, constipation, depression.
Thyroid dysfunction is common and treatable. See a doctor for symptoms or screening if at risk.
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