Milia in Adults: Causes, Persistence, and Treatment Options
Milia are 1–2 mm keratin-filled epidermal cysts, commonly on the face (eyelids, cheeks, forehead). Unlike acne, they lack an opening to the surface.
Why They Persist in Adults
- No natural drainage pathway — keratin trapped below stratum corneum.
- Adult skin turnover slows; cysts stabilize rather than resolve.
- Contributing factors: heavy occlusive creams, sun damage, topical steroids, blistering injuries, genetic predisposition.
- Neonatal milia (common, resolve spontaneously) differ from adult primary/secondary milia.
Home Care Limitations
- Exfoliation (AHAs/BHAs, retinoids): May prevent new milia; rarely clears existing cysts.
- Topical retinoids (tretinoin, adapalene): Increase turnover; modest effect over months.
- Heavy creams: Can worsen by increasing occlusion.
- Do not squeeze: Causes inflammation, scarring, infection; cyst wall remains.
Professional Removal Methods
| Method | Mechanism | Best For | Downtime |
|---|---|---|---|
| Manual extraction (lancet/needle + comedone extractor) | Unroof cyst, express keratin core | Few lesions; eyelids | Minimal |
| Electrodesiccation / Hyfrecation | Light cautery to destroy cyst wall | Multiple, thicker cysts | 1–2 weeks crusting |
| Laser ablation (CO₂, Erbium:YAG) | Vaporize cyst | Numerous, diffuse; cosmetic precision | 3–7 days |
| Cryotherapy | Freeze-thaw destruction | Trunk/extremities; not face | Blistering, hypopigmentation risk |
| Chemical peels (TCA, Jessner's) | Epidermal resurfacing | Concurrent photoaging/milia | Days to weeks |
