| | Conditions & Treatments | Skin Conditions Which skin layer does the process of keratin begins? Keratinization, or the process of forming keratin, begins in the stratum basale, the deepest layer of the epidermis, which acts as the basal layer. Skin Conditions - Related Articles How to Get Moisture Back Into Your Skin How to Turn a Person in Bed for Pressure Relief What are three things you can do to keep your skin? How to Treat Cold Sore Scabs Psoriasis vs. Eczema: How to Tell the Difference How to Treat a Wood Splinter What is non intact skin?