Scleverma (Clobetasol Propionate) for Eczema: Efficacy, Usage, and Side Effects

Scleverma is a brand name for clobetasol propionate 0.05%, a super-high-potency (Class I) topical corticosteroid.

Indications

Short-term treatment of inflammatory, pruritic dermatoses responsive to steroids: eczema (atopic, contact, nummular), psoriasis, lichen planus, discoid lupus.

Usage

• Apply thin layer to affected areas twice daily (max 2 weeks for Class I; 4 weeks for lower potency).
• Avoid face, groin, axillae, inframammary folds (thin skin → atrophy, striae, telangiectasia, perioral dermatitis).
• Do not use under occlusion unless directed.
• Taper gradually after control to prevent rebound flare.

Side Effects

• Local: Skin atrophy, striae, telangiectasia, hypopigmentation, acneiform eruption, contact dermatitis.
• Systemic (rare with limited use): HPA axis suppression, Cushingoid features, hyperglycemia.

Cautions

Not for rosacea, perioral dermatitis, acne, fungal/bacterial/viral infections (unless combined with antimicrobial). Pregnancy Category C. Pediatric use requires specialist supervision.