Osteoarthritis vs. Rheumatoid Arthritis: Key Differences in Cause and Progression

Neither osteoarthritis (OA) nor rheumatoid arthritis (RA) is universally “worse”—both cause significant discomfort and disability. They differ in cause and progression.

Osteoarthritis (OA)

  • Most common arthritis type
  • Caused by cartilage wear and tear
  • Typically affects knees, hips, hands, spine
  • Pain and stiffness worsen over time
  • Primarily affects cartilage and bones

Rheumatoid Arthritis (RA)

  • Autoimmune disease
  • Immune system attacks joints
  • Can affect other organs and systems
  • Causes inflammation and joint damage
  • May lead to additional systemic complications

Both significantly impact quality of life. Treatment depends on severity, overall health, and patient preferences.

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