What causes caseous necrosis in lungs tissue?

Tuberculosis (TB):

- It is the classic example of caseous necrosis.

- TB is a chronic granulomatous disease caused by the bacterium _Mycobacterium tuberculosis_.

- The primary infection usually occurs in the lungs, where it induces the formation of granulomas.

- The granulomas may undergo central necrosis, leading to caseous necrosis.

Other infections:*

- Some fungal infections, such as aspergillosis and mucormycosis, can also lead to caseous necrosis in the lungs.

- Nocardiosis, a rare infection caused by the bacterium Nocardia.

Non-infectious causes:

- Infarction of the lung tissue can also result in caseous necrosis.

- Sarcoidosis, a disease of unknown etiology characterized by the formation of non-caseating granulomas in various organs, can sometimes show focal caseous necrosis in the lungs.

- Lung cancer can also cause areas of caseous necrosis within the tumor.