Top Three Health Risks of Overweight and Obesity

  1. Heart disease: Leading U.S. killer. Excess weight → hypertension, dyslipidemia, insulin resistance → atherosclerosis.
  2. Stroke: 5th leading cause. Obesity promotes thrombosis, hypertension, dyslipidemia, diabetes—all stroke risks.
  3. Type 2 diabetes: Obesity is the primary driver. Adipose tissue causes insulin resistance → hyperglycemia → micro/macrovascular complications.

Weight loss of 5–10% significantly reduces all three risks. Comprehensive lifestyle intervention is first-line therapy.

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