Steven-Johnson Syndrome (SJS): Causes, Symptoms & Treatment

Steven-Johnson syndrome (SJS), also known as erythema multiforme major, is a rare, serious skin condition that affects the skin and mucous membranes. It can be triggered by certain medications, infections, or allergic reactions.

SJS is characterized by:

- A widespread, painful rash that can cover large areas of the body

- Blisters that can form on the skin and mucous membranes of the mouth, nose, eyes, and genitals

- Fever

- Difficulty swallowing

- Painful urination

- Severe weakness and fatigue

- Low blood pressure

SJS can be life-threatening and requires immediate medical attention. Treatment typically involves stopping the suspected trigger, providing supportive care, and treating any complications. In some cases, hospitalization is necessary.

SJS can be caused by a variety of factors, but some of the most common include:

- Medications: Certain medications, such as antibiotics, anti-inflammatory drugs, and seizure medications, can cause SJS.

- Infections: SJS can be triggered by infections such as influenza, herpes simplex, and Epstein-Barr virus.

- Allergic reactions: SJS can also be caused by allergic reactions to certain substances, such as foods or chemicals.

SJS is a serious condition, but it can be managed if it is treated promptly. If you experience any of the symptoms of SJS, it is important to see a doctor right away.