Parkinson's Disease: A Progressive Neurological Disorder

Parkinson's disease is a chronic, progressive neurodegenerative disorder affecting the central nervous system. It results from the loss of dopaminergic neurons in the substantia nigra, leading to dopamine deficiency.

Core Motor Symptoms

• Resting tremor
• Rigidity
• Bradykinesia (slowness of movement)
• Postural instability

Epidemiology

Parkinson's is the second most common neurodegenerative disease after Alzheimer's, typically presenting after age 60.

While no cure exists, medications (levodopa, dopamine agonists), deep brain stimulation, and rehabilitative therapies can significantly improve quality of life.