Cardiorenal: Heart-Kidney Interactions in Health & Disease

Cardiorenal = pertaining to both heart and kidney.

Cardiorenal Syndrome (CRS) – 5 subtypes describing bidirectional organ dysfunction:

1. Type 1: Acute cardiac → acute kidney
2. Type 2: Chronic cardiac → chronic kidney
3. Type 3: Acute kidney → acute cardiac
4. Type 4: Chronic kidney → chronic cardiac
5. Type 5: Systemic disorder → both

Shared pathways: neurohormonal (RAAS, SNS), inflammation, venous congestion, anemia.