Kidney Infection (Pyelonephritis): Mild to Life-Threatening Severity Grades

Pyelonephritis severity spectrum:

  • Mild: low-grade fever, flank pain, dysuria; outpatient oral antibiotics.
  • Moderate: high fever, rigors, nausea/vomiting, dehydration; IV antibiotics, fluids.
  • Severe: sepsis, septic shock, AKI, altered mental status; ICU care, broad-spectrum IV antibiotics, vasopressors.

Complications: renal abscess, papillary necrosis, emphysematous pyelonephritis, CKD. Prompt treatment prevents scarring.

Kidney Disease - Related Articles