Unexplained Infertility: Causes, Symptoms & What to Do

Unexplained infertility is a medical condition in which a couple has been unable to conceive a child even though they are both fertile and have regular sexual intercourse without contraception. Unexplained infertility accounts for approximately 10-20% of all infertility cases.

There are many possible causes of unexplained infertility. Some potential factors include:

- Immunological issues, such as an immune system response that prevents the sperm from fertilizing the egg

- Genetic factors, such as defects in the genes that control fertility

- Ovulation problems, such as irregular ovulation or anovulation

- Sperm problems, such as low sperm count, poor sperm motility, or abnormal sperm morphology

- Endometriosis, a condition in which tissue similar to the lining of the uterus grows outside the uterus

- Polycystic ovary syndrome, a hormonal imbalance that affects ovulation

- Pelvic inflammatory disease, an infection of the uterus, fallopian tubes, or ovaries

If you are experiencing unexplained infertility, your doctor may recommend a variety of tests and procedures to identify the cause of your infertility and develop a treatment plan. Treatment for unexplained infertility may include medications, surgery, assisted reproductive technologies (such as in vitro fertilization, or IVF), or a combination of these approaches.