Diphtheria Vaccine: DTaP for Children, Tdap for Adults

Diphtheria vaccine is always given as a combination:

  • DTaP: Pediatric (6 weeks–6 years); 5 doses (2, 4, 6, 15–18 mo, 4–6 yr). Higher diphtheria/pertussis antigen.
  • Tdap: Adolescent/adult booster (11–12 yr, then every 10 yr); also each pregnancy (27–36 wk). Lower diphtheria/pertussis antigen.
  • Td: Tetanus/diphtheria only; if pertussis contraindicated.

Diphtheria is rare in vaccinated populations but remains a threat in underimmunized communities. Boosters maintain protection.

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