Complement System vs. Antibodies: Key Differences Explained

The statement that complement cells produce antibodies is incorrect. Here's the distinction:

Antibodies

  • Produced by plasma cells (differentiated B lymphocytes).
  • Part of the adaptive immune response; they recognize specific antigens.

Complement System

  • Consists of a cascade of proteins (not cells) that enhance the ability of antibodies and phagocytic cells to clear pathogens.
  • Acts as part of the innate immune system; it does not produce antibodies.
  • Functions include opsonization, inflammation, and direct lysis of microbes via the membrane attack complex.

In short, antibodies are specialized proteins made by B cells, while the complement system is a group of proteins that work alongside antibodies to destroy invaders.

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