Peribronchial Inflammation: Causes, Symptoms & Treatment

Peribronchial inflammation (also peribronchitis) refers to inflammation of the connective tissue and mucosa surrounding the bronchi (medium-sized airways). It is a descriptive term, not a specific disease.

Causes

  • Respiratory infections (bronchitis, pneumonia)
  • Allergic reactions (pollen, dust mites, pet dander)
  • Environmental irritants (smoke, pollutants, chemicals)
  • Autoimmune disorders (asthma, sarcoidosis)
  • Chronic respiratory diseases (COPD, bronchiectasis)

Symptoms

  • Persistent cough (dry or productive)
  • Wheezing (especially on exhalation)
  • Shortness of breath on exertion
  • Chest tightness or discomfort
  • Increased mucus production

Diagnosis

Clinical history, physical exam (auscultation), imaging (CXR, CT), and pulmonary function tests.

Treatment

Target the underlying cause: bronchodilators, inhaled corticosteroids, antibiotics (if infection), allergen avoidance, and in severe cases, supplemental oxygen.

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