What is Dehydroepiandrosterone Sulfate?

Dehydroepiandrosterone (DHEA) is an androsterone secreted by the adrenal glands. Small quantities are secreted by the brain, skin, testes and ovaries. DHEA is a precursor molecule and is converted into hormones such as estrogen and testosterone. It is the most abundant steroid hormone circulating in the human body.

DHEA May Benefit Women

• A statistically significant correlation between higher levels of DHEA and bone density in postmenopausal women suggests DHEA might help prevent bone loss. Abnormally low concentrations of DHEA have been found in women diagnosed with breast cancer; however, more studies are needed to investigate the possible correlation.

Anti-Obesity Factor of DHEA

• DHEA may positively influence glucose metabolism and decrease appetite. DHEA may help prevent obesity and diabetes as a result. Studies of animal models have yet to be applied to humans.

DHEA May Affect Neurons and Neurotransmitters

• Abnormally low concentrations of DHEA are found in Alzheimer's and dementia patients as well. Many of the specific actions of DHEA are not yet well understood; however, it is known to stabilize the growth of nerve cells. As of October 2010, oral supplements of DHEA are being tested on Alzheimer's patients.

Natural DHEA Production

• The amount of DHEA produced decreases with age. At age 20 the body produces approximately 30 mg of DHEA per day; by age 80, only 6 mg are produced. For this reason, many take DHEA as an oral supplement in the form of dehydroepiandrosterone sulfate.