FSH vs. Testosterone: Distinct Hormones, Different Roles

Follicle-stimulating hormone (FSH) and testosterone are not the same.

  • FSH (anterior pituitary): In males, stimulates Sertoli cells → spermatogenesis. In females, drives follicular growth and estradiol production.
  • Testosterone (Leydig cells in testes; ovaries/adrenals in females): Primary androgen; mediates male secondary sexual characteristics, libido, muscle/bone mass, and in women, contributes to ovarian function and libido.

They interact: FSH and LH stimulate testosterone production; testosterone negatively feeds back on FSH/LH.

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