What antibody fights the HIV VIrus?
The Broadly Neutralizing Antibodies (bnAbs) are a group of antibodies that fight against a wide range of HIV viruses. These bnAbs are produced by the body's immune system in response to HIV infection. They are able to recognize and bind to specific proteins on the surface of the HIV virus, preventing the virus from infecting and destroying healthy cells in the body. Some of the most well-known bnAbs include:
* VRC01: This antibody was isolated from a patient who had been infected with HIV for over 20 years without developing AIDS. VRC01 is able to bind to a highly conserved region of the HIV envelope protein, making it effective against a wide range of HIV strains.
* PG9: This antibody was isolated from a patient who had been infected with HIV for over 10 years without developing AIDS. PG9 is able to bind to a different region of the HIV envelope protein than VRC01, making it effective against a complementary set of HIV strains.
* Pgt121: This antibody was isolated from a patient who had been infected with HIV for over 15 years without developing AIDS. Pgt121 is able to bind to a third region of the HIV envelope protein, making it effective against a different set of HIV strains than VRC01 and PG9.
These bnAbs are currently being studied as potential treatments for HIV infection. They offer the potential to provide long-lasting protection against the virus and could potentially lead to a cure for HIV.
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