HIV and Blood Type: No Natural Immunity Exists

There is no scientific evidence that any blood type provides protection against HIV infection. People of all blood types (A, B, AB, O) can contract HIV if exposed to the virus through blood, sexual fluids, or mother-to-child transmission.

The virus infects CD4+ T cells via specific receptors (CD4, CCR5/CXCR4), which are present regardless of ABO blood group. While certain genetic variations (like CCR5-Δ32 mutation) can affect susceptibility, these are unrelated to blood type.

Prevention relies on proven methods: condoms, PrEP, sterile needles, treatment as prevention (U=U), and regular testing—not blood type.