Blood Pressure Is Normally Consistent Throughout the Body, With Minor Gravitational Fluctuations

Systemic arterial pressure is generated by the left ventricle and transmitted throughout the arterial tree. At the same vertical level, pressure is nearly identical (within measurement error).

Hydrostatic gradient: ~0.77 mmHg per cm vertical height difference (blood density ~1.06 g/mL).

  • Arm (heart level) vs. leg (standing): ~80–100 mmHg higher in leg due to gravity.
  • Supine: Arm ≈ leg (same horizontal plane).
  • Clinical implication: Measure BP at heart level (arm supported). Ankle-brachial index (ABI) compares systolic ankle/arm to assess PAD, not absolute leg pressure.

Pathologic discrepancies (e.g., subclavian stenosis, coarctation, aortic dissection) cause true inter-arm or arm-leg gradients. Routine bilateral BP measurement detects these.

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