What is a normal hemoglobin AA sequence?
The normal hemoglobin A sequence (also called Hb A0 or Hb A) consists of four polypeptide chains: two alpha chains and two beta chains. Each chain is composed of a specific sequence of amino acids.The alpha chain of Hb A contains 141 amino acids and has the following sequence:
```
VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
```
The beta chain of Hb A contains 146 amino acids and has the following sequence:
```
VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
```
These sequences represent the primary structures of the alpha and beta chains of Hb A. The complete hemoglobin molecule is formed by the assembly of these chains into a tetrameric structure.
Hemorrhage - Related Articles
- Where blood is oxygenated?
- Will a heterozygous female with hemophilia have blood that will clot normally?
- What is a haemacell?
- Why are the antecubital veins preferred for performing venipuncture?
- How to Recognize the Symptoms of a Pulmonary Hemorrhage
- What do you in case of bleeding?
- How does hemoglobin help with carbon dioxide transport?
