Can thin blood affect you spleen?

The answer is: no

The spleen is not affected by thin blood. Thin blood is related to a low red blood cell count. Anemia may be a cause of thin blood. There are several reasons behind anemia such as low dietary intake of essential nutrients e.g., iron for iron deficiency anemia or deficiency of Vitamin B12 and folate, genetic mutations like mutations of hemoglobin in sickle cell anemia. The spleen functions to store red blood cells.