Top 10 Most Addictive Substances in the U.S. | SAMHSA Data

According to the Substance Abuse and Mental Health Services Administration (SAMHSA), the top 10 substances of misuse in the United States are:

1. Marijuana

2. Alcohol

3. Prescription opioids

4. Heroin

5. Cocaine

6. Methamphetamine

7. Stimulants

8. Hallucinogens

9. Inhalants

10. Nicotine

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