Effective Pain Relief for Piriformis Syndrome: Medications & Options

Piriformis syndrome occurs when the piriformis muscle presses on the sciatic nerve. This narrow muscle is located deep in the buttocks. The pain may be referred to a sciatica pain.
  1. Effects

    • Piriformis syndrome is characterized by pain, tingling and numbness in the buttocks and legs.

    Over-the-Counter Pain Medications

    • According to Spine Health, naproxen or Ibuprofen are often enough to combat piriformis syndrome pain. While anti-inflammatory medications do not target pain specifically, they can bring about pain relief by reducing swelling and inflammation that may be causing pain.

    Prescription Pain Medications

    • Pain may be alleviated with prescription-strength ibuprofen or muscle relaxers.

    Other Medications

    • Corticosteroid injections may reduce severe piriformis pain quickly; however, injections typically only provide temporary relief and may need to be repeated at regular intervals.

    Other Treatments

    • Stretching exercises and massage may be beneficial in treating piriformis syndrome. Severe cases may require surgery.

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