Iritis (Anterior Uveitis) Treatment: Medications, Laser, and Surgery
Iritis (anterior uveitis) is inflammation of the iris. Treatment targets inflammation control, pain relief, and complication prevention.
Therapeutic Options
- Topical corticosteroids (prednisolone acetate 1%, difluprednate) – mainstay; frequency tapered by response.
- Cycloplegic/mydriatic agents (cyclopentolate, atropine) – relieve ciliary spasm (photophobia/pain), prevent posterior synechiae (iris-lens adhesions).
- Systemic therapy (oral corticosteroids, immunosuppressants, biologics) – for severe, recurrent, or systemic-associated (e.g., HLA-B27, sarcoidosis, IBD) cases.
- Laser (Nd:YAG) iridotomy/synechialysis – for established synechiae or pupillary block glaucoma.
- Surgery – cataract extraction, vitrectomy, or glaucoma surgery for complications.
Monitoring
Regular slit-lamp exams for cell/flare, IOP, synechiae, cataract. Early referral to uveitis specialist improves outcomes.
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