Squamoproliferative Lesions: Causes, Types & Treatment
Squamoproliferative lesions are abnormal growths of squamous cells (epidermal keratinocytes), ranging from benign to malignant.
Causes
- HPV infection (types 6, 11, 16, 18) → warts, some cancers.
- UV radiation → actinic keratosis (precancerous).
- Immunosuppression (HIV, transplant meds).
- Genetic disorders (epidermodysplasia verruciformis).
Common Types
- Warts: HPV-induced fleshy growths.
- Actinic keratosis: Rough, scaly sun-damaged patches.
- Squamous cell carcinoma: Malignant tumor from squamous cells.
Diagnosis & Treatment
Clinical exam ± biopsy. Treatment: topicals, surgical excision, laser, depending on type/severity. Early evaluation improves outcomes.
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