| | Conditions & Treatments | Diseases What does mal mean as a medical term? The medical term "mal-" is a prefix that means "bad" or "abnormal." It is often used to describe a condition or disease that is characterized by pain, discomfort, or dysfunction. Diseases - Related Articles How to Set Realistic Goals for Children With Cerebral Palsy Gallbladder Pain Symptoms What is the most common treatment for rosacea? Healthy Liver Function What does the disease was ceaseless mean? Diet for Glandular Fever Which Diseases Do Fleas Carry?