Fluocinonide for Staph Infection: Not Effective

Fluocinonide 0.05% is a potent topical corticosteroid. It reduces inflammation but has no antibacterial activity. Staph infections require antibiotics (topical or systemic). Using steroids alone on bacterial infections can worsen them by suppressing local immunity.

If you suspect a staph infection (honey-colored crusts, spreading redness, warmth, pus), see a clinician for appropriate antibiotic therapy.