Understanding Staphylococcal Coagulase: Types and Functions
The two main types of staphylococcal coagulase are:
- Bound coagulase: This type of coagulase is bound to the surface of the bacterial cell and is responsible for the clumping of plasma. It is also known as clumping factor or cell-bound coagulase.
- Free coagulase: This type of coagulase is secreted into the extracellular environment and is responsible for the conversion of fibrinogen to fibrin. It is also known as staphylocoagulase or extracellular coagulase.
Both bound and free coagulase are important virulence factors that contribute to the pathogenesis of Staphylococcus aureus infections.
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