Transfusion Reactions: Severity, Types, and Outcomes

Transfusion incompatibility reactions are not always fatal. Severity depends on incompatibility type, blood volume, and recipient immune status.

  • Immediate hemolytic reactions: Most severe; rapid RBC destruction → kidney failure, DIC, death.
  • Non-hemolytic reactions (allergic, febrile): Generally mild, not life-threatening.

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