Can you take allergy medicine while on a z pak?

Yes, it is generally safe to take allergy medicine like loratadine (Claritin) or cetirizine (Zyrtec) with a Z-Pak (azithromycin), an antibiotic medication. However, it is always a good idea to consult with your doctor or pharmacist before taking any new medication, especially if you have pre-existing medical conditions.