Disulfiram and Sulfur Allergy: A Critical Interaction

No, a person with a sulfur allergy should not use disulfiram.

Disulfiram is a medication used to treat alcohol dependence. It works by inhibiting the enzyme aldehyde dehydrogenase, which is responsible for breaking down alcohol in the body. This causes the accumulation of acetaldehyde, which is a toxic substance that causes unpleasant symptoms such as nausea, vomiting, flushing, and headache. Disulfiram is contraindicated in people with a known allergy to sulfur or thiuram.