Is it necessary to take the DNA test of donor in case his bone marrow is taken for transplantation?

Yes, it is necessary to take the DNA test of the donor in case their bone marrow is taken for transplantation. This is done to ensure that the donor and the recipient are a good match for the transplant.

A DNA test can help determine:

- Tissue compatibility: The DNA test helps assess the compatibility of the donor's and recipient's tissue. It ensures that the donor's immune system will not reject the recipient's cells, thereby reducing the risk of graft-versus-host disease (GVHD).

- Disease risk: The DNA test can help identify potential genetic disorders or diseases that the donor may carry, which could pose risks to the recipient post-transplantation. Early detection of such risks allows for appropriate medical management and precautions.

Matching the donor's and recipient's DNA closely improves the chances of successful engraftment, reduces the risk of rejection and GVHD, and ensures the long-term health of the recipient.