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Ovarian Size: Understanding Normal and Enlarged Ovaries
Ovaries are typically symmetric, each measuring approximately 3 cm × 1.5 cm × 1.5 cm (volume 4–6 mL) in reproductive‑age women. Size varies with age, cycle phase, and hormonal status.
Asymmetry or Enlargement may indicate:
- Physiologic: Dominant follicle (up to 2–3 cm mid‑cycle), corpus luteum cyst.
- Pathologic: Polycystic ovary morphology (PCOM—≥20 follicles 2–9 mm or volume >10 mL), endometrioma, dermoid cyst, cystadenoma, ovarian torsion, malignancy.
- Hormonal: Stimulation (fertility drugs), hyperthecosis.
Transvaginal ultrasound is the standard for measurement. If an ovary is persistently enlarged, asymmetric, or has complex features, further evaluation (serial ultrasound, tumor markers CA‑125/HE4, MRI, referral to gynecologic oncology) is indicated.
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