| | Cancer | Ovarian Cancer
Menstruation and Ovulation After Bilateral Oophorectomy: Absent
Bilateral oophorectomy (removal of both ovaries) causes surgical menopause.
- No ovulation – no oocytes remain.
- No menstruation – no ovarian estrogen/progesterone → no endometrial proliferation/shedding.
- Hormonal consequences – abrupt loss of estradiol, progesterone, testosterone → vasomotor symptoms, bone loss, urogenital atrophy, cardiovascular risk.
Management
- Hormone therapy (HT) – estrogen ± progestin (if uterus intact) until average natural menopause age (~51), then reassess.
- Non-hormonal options for symptoms if HT contraindicated.
- Bone density monitoring, cardiovascular risk reduction.
If uterus remains, cyclic progestin induces withdrawal bleeding but this is not a true period (no ovulation).
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