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Menstruation and Ovulation After Bilateral Oophorectomy: Absent

Bilateral oophorectomy (removal of both ovaries) causes surgical menopause.

  • No ovulation – no oocytes remain.
  • No menstruation – no ovarian estrogen/progesterone → no endometrial proliferation/shedding.
  • Hormonal consequences – abrupt loss of estradiol, progesterone, testosterone → vasomotor symptoms, bone loss, urogenital atrophy, cardiovascular risk.

Management

  • Hormone therapy (HT) – estrogen ± progestin (if uterus intact) until average natural menopause age (~51), then reassess.
  • Non-hormonal options for symptoms if HT contraindicated.
  • Bone density monitoring, cardiovascular risk reduction.

If uterus remains, cyclic progestin induces withdrawal bleeding but this is not a true period (no ovulation).

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