Labetalol and Oral Side Effects: Dry Mouth, Not Inflammation

Labetalol (alpha/beta blocker) does not typically cause oral mucosal inflammation. The most common oral side effect is xerostomia (dry mouth), dose-related, due to reduced salivary flow from sympathetic blockade. This can increase caries risk and discomfort. Management: hydration, sugar-free gum/lozenges, saliva substitutes, fluoride. Report persistent oral symptoms to prescriber to exclude other causes (lichen planus, candidiasis, drug reactions).