Mesoglycan: Properties, Benefits, and Therapeutic Potential

Mesoglycan is an exopolysaccharide (EPS) produced by the Gram-positive bacterium Bacillus subtilis. It consists of repeating glucose and mannose units (46 glucose : 7 mannose). Demonstrated properties:

• Anticoagulant: Inhibits blood clot formation in vitro and in vivo; potential for thrombosis prevention/treatment.
• Anti-inflammatory: Reduces inflammation in animal models; may inhibit pro-inflammatory cytokines (TNF-alpha, IL-1 beta).
• Antioxidant: Scavenges free radicals; potential for oxidative stress conditions (cancer, neurodegenerative diseases).
• Immunomodulatory: Modulates immune system by stimulating and suppressing responses; interacts with macrophages, dendritic cells, T cells.

Mesoglycan is a promising natural product with therapeutic potential; further research needed to fully understand mechanisms and develop effective formulations.