Lymph Node Anatomy: The Medulla and Its Cellular Components
The medulla is the central, inner region of a lymph node. It contains:
- Lymphocytes (B cells, T cells)
- Macrophages
- Dendritic cells
- A network of blood vessels and medullary sinuses that filter lymph before it exits via efferent vessels.
The medulla is where activated lymphocytes proliferate and differentiate, and where antibody-secreting plasma cells often reside. Understanding its structure helps in interpreting lymph node pathology.
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