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Lymph Node Cancer Survival Rates: Hodgkin vs. Non-Hodgkin Lymphoma

The overall 5-year survival rate for all lymph node cancers (lymphomas) is approximately 70%, but prognosis varies significantly by type and stage.

Hodgkin Lymphoma

Hodgkin lymphoma has one of the highest cure rates among cancers.

  • All stages combined: ~85% 5-year survival
  • Early stage (I or II): ~95% 5-year survival
  • Advanced stage (III or IV): ~80% 5-year survival

Non-Hodgkin Lymphoma (NHL)

NHL encompasses many subtypes with widely varying outcomes.

  • Indolent (slow-growing) lymphomas (e.g., follicular, small lymphocytic): 70-80% 5-year survival; often managed as chronic disease.
  • Aggressive (fast-growing) lymphomas (e.g., diffuse large B-cell, Burkitt): 50-60% 5-year survival; potentially curable with intensive chemotherapy.

Improving Trends

Survival rates have risen steadily due to advances in chemotherapy, immunotherapy (e.g., CAR-T cells), targeted therapy (e.g., BTK inhibitors), and radiation techniques. Early diagnosis and subtype-specific treatment are key.

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