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Cancer Treatment Options: A Comprehensive Overview
Optimal cancer therapy is personalized, based on tumor type, stage, molecular profile, patient health, and preferences. A multidisciplinary tumor board typically designs the plan.
Major Modalities
- Surgery: Primary resection for localized solid tumors; often curative in early stages.
- Radiation Therapy: High‑energy beams (photons, protons) damage DNA; used as definitive, adjuvant, or palliative treatment.
- Chemotherapy: Cytotoxic drugs targeting rapidly dividing cells; systemic; neoadjuvant, adjuvant, or palliative.
- Targeted Therapy: Small molecules or antibodies against specific oncogenic drivers (e.g., EGFR, HER2, BCR‑ABL, ALK).
- Immunotherapy: Checkpoint inhibitors (PD‑1/PD‑L1, CTLA‑4), CAR‑T cells, cancer vaccines—harness immune system.
- Hormone Therapy: For hormone‑receptor‑positive breast/prostate cancers (anti‑estrogens, aromatase inhibitors, androgen deprivation).
- Stem Cell Transplant: Autologous/allogeneic rescue after high‑dose chemo for hematologic malignancies.
Emerging Approaches
- Antibody‑drug conjugates, bispecific antibodies, oncolytic viruses, microbiome modulation.
Follow‑Up
Regular imaging, tumor markers, and clinical assessment to monitor response, detect recurrence, and manage late effects.
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